Thursday, 20 June, 2024

Physical properties of S-adenosyl-L-methionine disulfate tosylate

S-adenosyl-L-methionine (SAM or AdoMet) is a central molecule in biochemistry, acting as a universal methyl donor in various biological processes. The disulfate tosylate derivative of SAM is a synthetic compound that has garnered attention for its potential applications in chemical biology and medicinal chemistry. SACH will share the physical properties of S-adenosyl-L-methionine disulfate tosylate for sale, a topic of significant interest to researchers in the field.

Structural Overview

Before we explore the physical properties, let's briefly discuss the structure of SAM disulfate tosylate. It is derived from SAM by the addition of a tosylate group to the sulfur atoms of the disulfide bridge. This modification can affect the compound's reactivity, solubility, and interaction with enzymes and other biomolecules.

Molecular Weight and Formula

The molecular weight of SAM disulfate tosylate is a critical physical property that influences its behavior in chemical reactions and its transport across biological membranes. The molecular formula, incorporating the tosylate group, adds to the complexity and weight of the original SAM molecule.

Solubility Profile

Solubility is a key physical property that determines how well SAM disulfate tosylate can dissolve in various solvents, which is essential for its use in assays and biological systems. The tosylate group generally enhances solubility in organic solvents, whereas the adenosyl and methionine moieties contribute to its solubility in aqueous environments.


Melting Point and Boiling Point

The melting and boiling points of SAM disulfate tosylate are indicative of the strength of the intermolecular forces within its crystal lattice. These temperatures are influenced by the size and shape of the molecule, as well as the presence of the tosylate group, which can introduce additional van der Waals forces.

Stability and Reactivity

The stability of SAM disulfate tosylate under different conditions, such as varying pH levels or temperatures, is crucial for its practical application. The compound's reactivity with various nucleophiles and electrophiles is also of interest, as it can affect its utility as a synthetic intermediate or a probe in biochemical research.

Optical Properties

The optical properties of SAM disulfate tosylate, including its absorption and fluorescence spectra, can provide insights into its electronic structure and potential use as a fluorescent tag or in photochemical reactions.

Conductivity and Electrochemical Properties

For applications involving electrochemistry, the conductivity of SAM disulfate tosylate and its redox potential are important physical properties. These characteristics can influence its behavior in electrochemical cells and its use in the development of biosensors.

Thermal Analysis

Thermal analysis techniques such as differential scanning calorimetry (DSC) and thermogravimetric analysis (TGA) can provide information about the compound's thermal stability and decomposition pathways, which are valuable for its formulation and long-term storage.

Mechanical Properties

While not typically a focus for small molecules, the mechanical properties of SAM disulfate tosylate in its solid-state form can be relevant if it is incorporated into materials science applications, such as in the development of drug delivery systems.

Biological Interactions

Although not a traditional physical property, the interaction of SAM disulfate tosylate with biological systems is a critical aspect of its physical behavior in a cellular context. This includes its membrane permeability, protein binding affinity, and potential to act as a substrate or inhibitor for various enzymes.


Understanding the physical properties of S-adenosyl-L-methionine disulfate tosylate is essential for its application in chemical biology and medicinal chemistry. From solubility to stability and reactivity, each characteristic plays a role in determining how this compound can be utilized in research and therapeutic development.


0 comments on “Physical properties of S-adenosyl-L-methionine disulfate tosylate

Leave a Reply

Your email address will not be published. Required fields are marked *